The interaction between famotidine and Pb²⁺ was investigated using direct current polarography. The polarographic technique was used to determine the stability constants and thermodynamic parameters such as enthalpy change (ΔH^#), free energy change (ΔG^#) and entropy change (ΔS^#) of Pb²⁺ complexes with famotidine. The study was carried out at two different temperatures 20 °C and 30 °C. Pb²⁺-famotidine complexes were formed in 1:1 and 1:2 ratios. The electrode processes were reversible and diffusion controlled.
Keywords: Stability Constant; Thermodynamic Parameters; Pb2+–Famotidine System